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taku
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City: Central FL
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 Posted: Nov 12, 2008 8:44 pm Post subject: American Aids patient cured in Germany!!! |
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Thank you Stem Cells!
So an American patient in Germany who had Leukemia and AIDS now all of a sudden is free of AIDS after getting a bone marrow transplant which was to help with his leukemia, ended up curing his aids and he's presently HIV negative. Watch the video for details. With more research into this case, we could be very close to finding the cure.
How would your life change if the cure for aids was found?
http://cosmos.bcst.yahoo.com/up/player/popup/?rn=3906861&cl=10647801&ch=4226714&src=news
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taku
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| Posted: Nov 12, 2008 8:47 pm Post subject: |
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DirtyCracker
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| Posted: Nov 12, 2008 8:47 pm Post subject: |
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| taku, i could finally start living and stop wondering when aids is going to take me away from this world |
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Le Jalapeno
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| Posted: Nov 12, 2008 8:54 pm Post subject: |
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taku, Goddamn!!!!!
funny pic
but seeing that just gave me a really warm feeling inside like there is something we can do.
of course it will be a long time before this is generalized and available to the masses, but still. |
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taku
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| Posted: Nov 12, 2008 8:55 pm Post subject: |
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People like Magic Johnson and otherwise rich people with good health care would be able to get treatment... but lets say a bone marrow transplant is necessary to treat aids... well Africans can't even afford the HIV cocktail to help treat it... let alone bone marrow transplants. But let's say it was available to everyone and AIDS was a thing of the past... as terrible as this is to say, could Africa even sustain all those mouths that would have otherwise died?
The pharmaceutical industry won't make as much money on helping cure anything like aids or cancer. There is more money to be had in ongoing treatment. 
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JeffKnox
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| Posted: Nov 12, 2008 8:57 pm Post subject: |
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thats insane... maybe we could do more stem cell research now ... the possibilities are endless
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taku
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| Posted: Nov 12, 2008 9:01 pm Post subject: |
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Thank you to Obama.. one of his first orders of business when he takes office is reverse Bush's policy on stem cell research! sweet.
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JeffKnox
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| Posted: Nov 12, 2008 9:06 pm Post subject: |
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taku, hopefully
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Le Jalapeno
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| Posted: Nov 12, 2008 9:07 pm Post subject: |
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| taku, I stole this and posted it on myspace, I hope you don't mind |
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edrex
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Joined: 18 Oct 2006
Posts: 1020
City: NorCal
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| Posted: Nov 12, 2008 9:48 pm Post subject: |
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Seriously, I'm more worried about the herps then AIDS, so this won't change my life much. But, glad to see someone somewhere is working on it.
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taku
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| Posted: Nov 12, 2008 10:20 pm Post subject: |
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Le Jap.. this is ground breaking IMO, everyone should know 
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Le Jalapeno
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| Posted: Nov 12, 2008 10:26 pm Post subject: |
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taku, Hence why I stole it  |
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scott a
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| Posted: Nov 12, 2008 11:39 pm Post subject: |
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According to the AP article this type of thing has already been done twice before, but is too costly/laborious to be practical in the real world.
| Quote: | German doctors say marrow transplant may have cured patient's AIDS; method still questionable
By PATRICK McGROARTY
The Associated Press
BERLIN
An American man who suffered from AIDS appears to have been cured of the disease 20 months after receiving a targeted bone marrow transplant normally used to fight leukemia, his doctors said Wednesday.
While researchers — and the doctors themselves — caution that the case might be no more than a fluke, others say it may inspire a greater interest in gene therapy to fight the disease that claims 2 million lives each year. The virus has infected 33 million people worldwide.
Dr. Gero Huetter said his 42-year-old patient, an American living in Berlin who was not identified, had been infected with the AIDS virus for more than a decade. But 20 months after undergoing a transplant of genetically selected bone marrow, he no longer shows signs of carrying the virus.
"We waited every day for a bad reading," Huetter said.
It has not come. Researchers at Berlin's Charite hospital and medical school say tests on his bone marrow, blood and other organ tissues have all been clean.
However, Dr. Andrew Badley, director of the HIV and immunology research lab at the Mayo Clinic in Rochester, Minn., said those tests have probably not been extensive enough.
"A lot more scrutiny from a lot of different biological samples would be required to say it's not present," Badley said.
This isn't the first time marrow transplants have been attempted for treating AIDS or HIV infection. In 1999, an article in the journal Medical Hypotheses reviewed the results of 32 attempts reported between 1982 and 1996. In two cases, HIV was apparently eradicated, the review reported.
Huetter's patient was under treatment at Charite for both AIDS and leukemia, which developed unrelated to HIV.
As Huetter — who is a hematologist, not an HIV specialist — prepared to treat the patient's leukemia with a bone marrow transplant, he recalled that some people carry a genetic mutation that seems to make them resistant to HIV infection. If the mutation, called Delta 32, is inherited from both parents, it prevents HIV from attaching itself to cells by blocking CCR5, a receptor that acts as a kind of gateway.
"I read it in 1996, coincidentally," Huetter told reporters at the medical school. "I remembered it and thought it might work."
Roughly one in 1,000 Europeans and Americans have inherited the mutation from both parents, and Huetter set out to find one such person among donors that matched the patient's marrow type. Out of a pool of 80 suitable donors, the 61st person tested carried the proper mutation.
Before the transplant, the patient endured powerful drugs and radiation to kill off his own infected bone marrow cells and disable his immune system — a treatment fatal to between 20 and 30 percent of recipients.
He was also taken off the potent drugs used to treat his AIDS. Huetter's team feared that the drugs might interfere with the new marrow cells' survival. They risked lowering his defenses in the hopes that the new, mutated cells would reject the virus on their own.
Anthony Fauci, director of the National Institute of Allergy and Infections Diseases in the U.S., said the procedure was too costly and too dangerous to employ as a firstline cure. But he said it could inspire researchers to pursue gene therapy as a means to block or suppress HIV.
"It helps prove the concept that if somehow you can block the expression of CCR5, maybe by gene therapy, you might be able to inhibit the ability of the virus to replicate," Fauci said.
David Roth, a professor of epidemiology and international public health at the London School of Hygiene and Tropical Medicine, said gene therapy as cheap and effective as current drug treatments is in very early stages of development.
"That's a long way down the line because there may be other negative things that go with that mutation that we don't know about."
Even for the patient in Berlin, the lack of a clear understanding of exactly why his AIDS has disappeared means his future is far from certain.
"The virus is wily," Huetter said. "There could always be a resurgence."
(This version CORRECTS spelling of doctor's name to Huetter throughout.)
Copyright 2008 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten, or redistributed. |
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